Microsomes: Structure and Function Explained kosheeka.com

Microsomes are small membrane-bound vesicles that are not found naturally as cell organelles. They are obtained in the laboratory via ultracentrifugation of the endoplasmic reticulum, which breaks apart during tissue homogenization. Although they do not naturally exist as independent structures in living cells, microsomes retain many of the enzymes found in the endoplasmic reticulum, particularly cytochrome P450 enzymes responsible for drug metabolism. Because of their rich enzymatic content, liver microsomes are widely used to study Phase I metabolic reactions, enzyme activity, and potential drug interactions, making them an indispensable tool in pharmacology and preclinical drug development. Kosheeka, India is a leading supplier of animal cell culture components. For detailed information,
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